By Jean-Louis Vincent
The yearly replace compiles the latest advancements in experimental and scientific examine and perform in a single accomplished reference publication. The chapters are written by way of good famous specialists within the box of in depth care and emergency drugs. it's addressed to every body concerned about inner medication, anesthesia, surgical procedure, pediatrics, extensive care and emergency medication.
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Additional info for Annual Update in Intensive Care and Emergency Medicine 2016
Accessed December 2015 31. Centers for Disease Control and Prevention (2014) Interim Infection Prevention and Control Recommendations for Hospitalized Patients with Middle East Respiratory Syndrome Coronavirus (MERS-CoV). gov/coronavirus/mers/infection-prevention-control. html. Accessed December 2015 32. Petrucci N, De Feo C (2013) Lung protective ventilation strategy for the acute respiratory distress syndrome. Cochrane Database Syst Rev 2:CD003844 33. Guerin C, Reignier J, Richard JC et al (2013) Prone positioning in severe acute respiratory distress syndrome.
There are, however, several opportunities to reduce unnecessary antibiotic exposure while preserving patient outcome. The principle of deescalation is currently the main answer to this diagnostic and therapeutic problem. However, it is important to tailor this principle to the individual clinical case and avoid unnecessary antibiotics as much as possible. This goal is best achieved by a dynamic approach with critical reassessments of the need for and choice of antibiotics at preset time points while actively pursuing diagnostics and integrating all the available information.
Conclusions and Future Directions More than three years after its identification, MERS-CoV remains a major global threat. Infection with MERS-CoV is frequently severe and associated with significant morbidity and mortality. Although our understanding of this virus and its disease continues to evolve, large knowledge gaps remain. The Arabian Peninsula remains the most affected region, but there is concern about the spread of this virus to other countries and globally. Until zoonotic transfer of the virus from animals to humans is stopped, the risk of additional domestic and perhaps international outbreaks persists.